Point of Care Reagent Blisters FAQs


What design services do you offer for reagent blisters?

J-Pac Mwdical offers a full range of design services to provide you with a turnkey solution. We work closely with you to understand the technical requirements for burst strength, activation, and other critical parameters and design a blister and manufacturing process based on those inputs. We are an FDA Registered, ISO 13485:2016 certified company with extensive expertise in blister design, material selection, and manufacturing. Other services include rapid prototyping, 3D modeling, Design of Experiments, Accelerated Shelf Life Testing, and Validation.

What materials do you offer?

We select materials based on the specific needs and reagent chemistry. For most applications, a multi-layered foil material is used that consists of a lidding foil and forming foil.

Blister Activation

What is the force required to actuate a blister?

The force required is greatly dependent on the actuation mechanism (e.g. lance, manual compression, etc). A general guideline is 30N +/- 15N.

What amount of fluid is recovered from the blister?

The amount of fluid recovered varies by the actuation and recovery method. A rule of thumb is 90% for common methods.

How do you actuate a blister?

We have experience in many actuation methods. Common approaches include lancing, mechanical compression, and rolling.


What volumes can be filled?

Filling is custom to the application. A general range is between 30-1,000 ?L.

Can you perform low oxygen filling?

We have proprietary filling technology that can achieve both 100% fill as well as extremely low O2 levels.

What is a common fill ratio?

A fill ratio of 80% full is common, resulting in a headspace ratio of 20%.


How do you mount the blisters?

Blisters are typically mounted using a pressure sensitive tape that is custom fit to the microfluidic cartridge.


What is your production capacity?

J-Pac has three ranges of production capacity. Our lab can supply small volumes of less than 5,000 units. Our semi-automated production lines can produce up to 5 million units per year. Our automated lines can produce more than 30 million units per year.

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